B6 (pyridoxine)
Vitamin B 6 is an essential nutrient; affects several key neurochemical processes of the brain, increasing the level of serotonin, dopamine, and y-aminobutyrate. Supports the immune system optimizing overall health. Low levels of B6 has been linked to depression.
Vitamin B6 is used by the body every single day and plays a major role in everything from movement to memory to energy expenditure and blood flow. Vitamin B6 also helps the body maintain a healthy nervous system, produces hemoglobin that carries oxygen in red blood cells throughout the body, aids in providing energy from the food that we eat, works to balance blood sugar levels, acts as a natural painkiller, boosts mood and also enhances immunity by increasing the synthesis of antibodies used to protect the body. However, the potential vitamin B6 benefits don’t stop there. In fact, studies show that vitamin B6 benefits can also maintain healthy blood vessels, reduce symptoms of rheumatoid arthritis, prevent kidney stones and more to help maximize your health.
B8 (Inositol)
Vitamin B8 (INOSITOL) is an abundant carbocyclic sugar in the brain
and other mammalian tissues that mediates cell signal transduction in response to a variety of hormones, neurotransmitters, and growth factors. Inositol may help balance important chemicals in your brain, including those believed to affect your mood, such as serotonin and dopamine. It is known for promoting the overall well-being of the brain; it helps maintain GABA health and serotonin metabolism. Increases cognitive function and at
B9 (Folate; Folic Acid)
Folate is clinically proved to have a relevant role in neurological manifestations;
it optimizes cerebral energy metabolism. Cognitive impairment, neurodegenerative disorders such as dementia, and depression, are scientifically linked to Vitamin B9 deficiency. The interactions between B9 and B12 (also present in this formula) vitamins have a significant role in the Central Nervous System (CNS) at all ages of human development. As part of the B Group Vitamin (BGV), folate has a key role in multiples metabolic pathways related to the CNS’s structural and functional integrity. Studies has confirmed that folate intake above 15mg for 6 months, has significantly improved clinical and social recovery in patients with schizophrenia and depression.
B12 (Methylcobalamin)
Vitamin B12, or metylcobalamin (the active form of B12), is a B vitamin necessary for cardiovascular and cognitive health.
It helps produce hemoglobin, improve nerve strength and regulate homocysteine levels. Homocysteine is an amino acid produced by the body, which in large amounts can increase the risk for heart attacks and strokes. Vitamin B12 works by making sure that your body uses the homocysteine in your blood.
Unfortunately, the human body cannot produce vitamin B12, and mainly depends on your diet to get ample supply. Vitamin B12 is naturally produced by anaerobic microorganisms commonly found in the gastrointestinal tract of animals. This means that the majority of B12 sources are either meat or poultry products, which is why many vegetarians and vegans are typically lacking this nutrient.
Vitamin B12 deficiency is positively linked to several neuropsychiatric disorders, including anxiety, panic disorder (PA), and depression. Studies suggests that B12 helps to prevent cognitive decline and depressive symptoms in adults; it facilitates potential efficacy in terms of overall cognitive and psychological performance. B12 is crucial for the adequate development and function of the brain, nerves, blood, and much more. It increases energy, focus, concentration, and boosts mood. But why is vitamin B12 necessary? Aside from being essential for cognition and brain health maintenance, it can also help you achieve peak health.
Vitamin C (Ascorbic Acid)
Vitamin C plays a significant role in the differentiation and maturation of neurons and in the formation of the myelin sheath.
This is the fatty layer that encapsulates the neuro axon, which speeds the electrical impulse through saltatory transmission and facilitates synaptic density. According to extensive studies, vitamin C is involved in the overall brain metabolism. Its deficiency is positively correlated to psychiatric pathologies playing a causative role in mental disorders, such as depression and anxiety disorders, and exacerbating its symptoms. Here are ten (10) more reasons we need Vitamin C:
1. Growth - Vitamin C helps in the formation of a protein that makes up the tissues of the body, like the tendons, ligaments, skin and blood vessels.
2. Antioxidant Protection - As a powerful antioxidant, vitamin C helps to defend the cells of the body against free radicals that can damage them and lead to illness, while also boosting the immune system.
3. Healing - Not only does vitamin C help to heal wounds on the soft tissues of the body by promoting the development of scar tissue, it also helps repair the teeth, bones and cartilage.
4. Disease Prevention - Daily intake of vitamin C can help lower your risk for developing certain cancers as well as heart disease and inflammatory conditions, including arthritis, by promoting collagen production.
5. Common Cold Fighter - While vitamin C hasn't been proven to directly prevent a common cold, it can help shorten the length of a cold and reduce the severity of symptoms. Anyone enduring intense physical exercise or exposed to extremely cold temperatures can especially benefit from vitamin C.
6. Healthy Hair - Vitamin C helps the hair retain moisture to prevent breakage or dryness. Having hair that's splitting or dry is a common sign of vitamin C deficiency.
7. Anti-Aging - Vitamin C is now a common ingredient in anti-aging creams, lotions and serums for preventing and improving the appearance of lines and wrinkles as well as dark spots. Most formulas have between five and 10 percent vitamin C.
8. Lower Blood Pressure - While research continues regarding vitamin C's effectiveness, it's been shown to support medications for lowering systolic blood pressure. The combination of the two being essential for results.
9. Iron Absorption - Iron is needed for maintaining healthy red blood cells and muscle tissue. Vitamin C has been shown to help the body absorb this important mineral more easily for better use throughout the body.
10. Arteries - Vitamin C can help protect the venous tone of the arteries, prevent atherosclerosis (hardening of the arteries) and lower the risk for developing peripheral arterial disease in women.
11. Mialyn sheath main ingredient - Vitamin C plays a role in the differentiation and maturation of neurons and in the formation of the myelin sheath that protects them and speeds impulse transmission, making the vitamin crucial to cognitive performance. It is a cofactor in the synthesis of several neurotransmitters, it's needed to convert dopamine to serotonin, and it modulates neurotransmitter release in nerve cells. And while it's long been known that the vitamin C is a component of collagen, a stabilizing force for teeth, bones, and blood vessels, only now is its role in ensuring blood vessel integrity seen as a factor in cognitive capacity, especially as we age.
In a recent review of 50 studies of vitamin C levels and cognitive function, all conducted between 1980 and January 2017, Australian researchers found a striking relationship between vitamin C status and mental function, as measured by a well-established questionnaire, the Mini Mental State Examination (MMSE). Those who were cognitively intact had significantly higher blood concentrations of vitamin C than those who were cognitively impaired. And among those who were cognitively intact, blood levels of vitamin C correlated with cognitive ability. No linear correlation was seen in those with cognitive impairment.
Severe vitamin C deficiency is known to cause scurvy. But scientists recognize that the human body needs far more than the minimal amount required to prevent the once-common disease. Just how much is necessary to support all body functions is not clear. Complicating matters is the fact that the amount consumed does not always translate into adequate blood levels. And factors like smoking, toxin exposure from air pollution, and alcohol consumption make extra demands for the nutrient as they place the body under oxidative stress. Studies have shown that such conditions as fatigue, depression, and poor wound healing are consequences of inadequate levels of vitamin C.
As little as 10 milligrams a day is needed to prevent scurvy. The RDA for adults is set at 90 mg/day for males, 75 mg/day for females. But vitamin C insufficiency is widespread.
A major longitudinal study of midlife adults underway in New Zealand, known as the CHALICE study, finds that 62 percent of 50-year-olds from all income levels, and more men than women, have inadequate blood concentrations of vitamin C. Almost all—93 percent—are below the optimal blood-saturation level for the nutrient. The researchers report that vitamin C status correlates with several markers of cognitive health as well as of metabolic health are correlated with lower levels of cognitive impairment. And even small increases in blood concentrations of the nutrient significantly reduced the odds of cognitive impairment. Those whose blood levels were below what the researchers believe is a minimal requirement for all functions had twice the likelihood of cognitive impairment as those who met it. Interestingly, rates of vitamin C inadequacy are higher in the United States than in New Zealand, the researchers report in the journal Nutrient.
An array of studies suggest that, day in, day out over the long haul, vitamin C plays some role in preventing the neural loss that typifies dementia, although studies of the vitamin as a treatment have proved equivocal. Researchers believe that it's long-term vitamin C status that matters, the amount of the antioxidant available over time.
Oxidative damage to the brain is pervasive in Alzheimer's disease and other forms of dementia. Oxidative stress activates an enzyme that cleaves beta amyloid from its precursor protein, accelerating amyloid production and setting the stage for its accumulation, one of the cardinal features of the disorder. Oxidative stress also impedes clearance of debris from brain cells, promoting the buildup of toxins, setting off inflammatory processes, and leading to cell death. Further, it impairs the ability of cells to utilize their glucose fuel.
Preserving brain function hinges on many factors, from physical exercise to stimulating activities to a fruit- and vegetable-rich diet. Consuming substantial amounts of vitamin C, especially starting in young adulthood, is part of that equation.
D3 (Cholecalciferol)
According to extensive studies, optimal levels of this highly-potent fat-soluble vitamin are directly related to mood regulation and brain accuracy.
Receptor for D3 vitamin in the brain are found in areas of the brain’s landscape that are related to mood disorders, attesting the positive correlation. Studies suggest that D3 vitamin is related to the levels of some monoamines, such as serotonin. Vitamin D3 plays a critical role in the absorption of phosphorus and calcium, which supports strong and healthy bones. Besides the bones, Vitamin D3 is important for immune and cardiovascular system, pancreas, muscles, brain, and the control of cell cycles.
High levels of Vitamin D3 have been linked to reduction of depression. A Norwegian trial found individuals taking vitamin D3 had a positive improvement in depression compared to the placebo group. In addition, in a study conducted by Kimball, Hu, and Walfish in 2004, subjects receiving Vitamin D3 had positive improvement in wellness over time was noted in treatment. The benefit of Vitamin D3 on depression is a cost effective therapy for persons at risk of depression. It is worth taking a walk outside in the sunshine, incorporating more vitamin D rich foods, and supplementing to reduces chances of depression.
Since there are very few foods that have natural accruing Vitamin D, supplementation may be necessary if one is deficient and doesn’t receive enough exposure to sunlight.
Omega 3 (Eicosapentaenoic and Docosahexaenoic Acids)
These fatty acids are known to enhance overall health, including mental health.
Researches had shown that Omega 3 deficiency is linked to some types of depressive disorders such as major depression, bipolar depression, minor depression, and postpartum depression, amongst others. Omega 3s have also been linked to prevention and attenuation of many others psychiatric disorders.
Low omega-3 levels have been reported in people with psychiatric disorders. Studies suggest that omega-3 supplements can reduce the frequency of mood swings and relapses in people with both schizophrenia and bipolar disorder.
Supplementing with omega-3 fatty acids, especially EPA (the most effective type to treat mental conditions- available on Neuropotential) may also decrease violent behavior. In addition, studies suggest that 3–6 grams of inositol associated with Omega 3 (both available on Neuropotential) taken daily may help reduce symptoms of psoriasis caused by lithium, a common medication used to treat bipolar disorder.
L-Tyrosine
This amino acid is the precursor of stimulatory neurotransmitters;
once metabolized, it is involved in the production of dopamine, adrenaline/norepinephrine. L-Tyrosine is a naturally occurring amino acid that is essential to both physical and mental function. It is the precursor for these three neurotransmitters, which are amongst the most important neurotransmitters in the brain.
Low level of these chemicals is related to depression, anxiety. Cognitive functioning such as mental accuracy and alertness, learning ability, and memory sharpness, especially during stressful or multi-tasking situations are also linked to L-Tyrosine.
L-tyrosine enhanced cognitive flexibility, the ability to switch between tasks or modalities of thought. This result was attributed mostly to the fact that L-tyrosine increases brain levels of dopamine, which is believed to control cognitive flexibility. Decades of studies show that supplemental L-tyrosine can significantly boost cognition in stressful conditions, effectively offsetting deficits in working memory and information processing created by environmental stressors such as extreme weather or intense cognitive demand.
By creating a “buffer” of raw material from which the brain can produce neurotransmitters, L-tyrosine supplementation may prevent the depletion that is associated with stress.
L-Glutamine
This essential amino acid promotes substantial benefits for mental functioning.
L-Glutamine, like glucose, acts like “fuel” for the brain, boosting its energy level. It also increases GABA levels favoring mental alertness, voluntary concentration, and enhancing memory. Studies found that optimal levels of L-Glutamine help to effectively combat depression and anxiety symptoms.
This amino acid is used to create proteins and is therefore involved in the composition of many protein products. Amongst other functions, it helps to create so-called amino sugars, which assist the body in combating problems like osteoarthritis. It also supports the production of glutathione.
Because this amino acid provides energy to the digestive cells, it aids those cells in their regeneration and renewal. Therefore, it supports the absorption ability of the intestine.
Cells which divide quickly, such as those in the immune system, are very reliant on having a good supply of L-glutamine. This is why medical procedures like bone marrow transplants have much lower death rates when a targeted supplementary regime containing this amino acid has been given beforehand. It can also protect human cells from destruction by free radicals. It is therefore able to, up to a certain point at least, prevent degenerative neurological illnesses like Alzheimer’s or Parkinson’s disease.
L-Taurine
This inhibitory amino acid serves various important functions on the central nerve system (CNS).
It is known for effectively boost the immune system and decrease anxiety, depression, psychosis symptoms, and promote overall health. It facilitates the production of GABA and helps to regulate cortisol and adrenalin spikes that are related to anxiety disorders and stress; thus, promoting the ideal chemical environment for anxiety regulation, stress management and mental fatigue improvement. It improves mental performance, including time-reaction, thought content, and attention.
Also, Taurine supplementation can prevent diabetes and obesity in animal models and can mitigate the effects of both conditions in humans. Taurine supplementation strengthens heart muscle cells, extends their life spans, and protects them from damage, while reducing many of the factors that produce atherosclerosis and its deadly consequences. Taurine protects retinal and inner ear cells from damage, normalizing the flow of calcium ions they require for proper function. Evidence is growing for L-taurine’s role in preventing epileptic seizures and liver disease, two conditions that can be attributed to toxic effects on delicate tissue.
If you are interested in a longer, healthier, and more active life, consider supplementing with taurine.
GABA (Gamma AminoButyric Acid)
GABA is a very important inhibitory neurotransmitter in the human central nerve system (CNS)
that binds to certain GABA receptor in the brain and instructs the neurons to stop firing- to stop a specific pattern of neuron excitability, triggering a calming effect; it is the brain’s natural tranquilizer. It calms the mind improving significantly mood, cognitive function, and inducing quality sleep. GABA’s big role in the body is to reduce overactivity of neurons in the brain and central nervous system, which in turn has a broad range of effects on the body and mind, including increased relaxation, reduced stress, a more calm, balanced mood, alleviation of pain, and a boost to sleep.
Low levels of GABA had been linked to anxiety, insomnia, attention deficiency disorder (ADD), attention deficiency and hyperactivity disorder (ADHD), panic disorder, obsessive compulsive disorder, and phobia disorder.
GABA promotes relieve for anxiety and stress, improves mood, reduces symptoms of premenstrual syndrome (PMS), and treats attention deficit-hyperactivity disorder (ADHD). It is also used for promoting lean muscle growth, burning fat, and for treating high blood pressure, motion sickness, cerebral palsy, bronchitis, Cushing's disease, epilepsy, Huntington's disease, meningitis, progressive brain disease caused by exposure to chemicals, and pain.
L-5-Hydroxytriptophan (5-HTP)
5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin (5-HT);
it is a precursor to serotonin. It increases the level of other neurotransmitters, including dopamine, norepinephrine and melatonin. The mood-enhancing chemical serotonin can affect memory, mood, attention, appetite, temperature, sleep, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, anxiety, panic disorder (PA), migraine headaches, mixed disorder of anxiety and depression, insomnia, obesity, and many other conditions. Some research has showed that, when taken along with another supplement called Gamma Aminobutyric Acid (GABA)- present in this formula- the combination of the two together might help people not only fall asleep faster but also sleep more restfully.
Magnesium Bisglycinate Chelate
Magnesium Bisglycinate Chelate is the latest magnesium chelate. Chelated simply means that the magnesium molecules are bonded to another molecule.
Chelation can improve a magnesium supplement’s stability, absorption, and bioavailability. Magnesium plays a critical role in more than 300 biochemical reactions in brain.
Magnesium is great as a muscle relaxant, and also has a calming effect - and it's is one of the many minerals that is generally deficient in our modern diet, which goes a long way to explaining the increased levels of anxiety we see today. Low levels of magnesium are associated with a whole range of disorders, including high blood pressure, diabetes and thyroid imbalances as well as anxiety, so a magnesium supplement makes sense if you have any of these conditions. Low levels of magnesium are related to neurological conditions including depression, panic disorder (PA), anxiety, ADHD, bipolar disorder, schizophrenia, phobias, addictions, acute brain injury, seizures, Parkinson’s disease, and Alzheimer’s disease.
Magnesium Bisglycinate Chelate can boost cognitive abilities and it’s particularly important for a healthy brain and nervous system: controls neuronal energy supply and enhances synapses’ density in the brain’s regions critical for executive functioning and memory. It prevents cognitive decline and reverses brain aging to nine years, according to recent studies. It exhibits anti-stress, anti-anxiety, anti-depressive and neuroprotective properties.
Iron
Recuperates neurotransmitters and enzymes that rely on iron.
It has a role in the syntheses of many enzymes and neurotransmitters of the central nerve system, including dopamine. Studies indicated that low serum concentration of B6 and Ferratin (iron) are involved with panic disorder (PD), hyperventilation attack (HVA), and depression. Ferratin and B6 play a significant role in the amalgamation of tryptophan into serotonin.
Iron is required for appropriate behavioral organization. Iron deficiency results in poor brain myelination and impaired monoamine metabolism. Glutamate and GABA (both present in Neuropotential) homeostasis is modified by changes in brain iron status. Such changes not only produce deficits in memory/learning capacity and motor skills, but also emotional and problems.
An accumulating body of evidence indicates that both energy metabolism and neurotransmitter homeostasis influence emotional behavior, and both functions are influenced by brain iron status. Like other neurobehavioral aspects, the influence of iron metabolism on mechanisms of emotional behavior are multifactorial: brain region-specific control of behavior, regulation of neurotransmitters and associated proteins, temporal and regional differences in iron requirements, oxidative stress responses to excess iron, sex differences in metabolism, and interactions between iron and other metals.
And this is why NEURO POTENTIAL is so effective!!!
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